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Downstream Processing

All common downstream processing methods are established from ml-scale to several hundred liters pilot scale for the development of robust and economical processes.

• Separation
  
• Cell lysis: chemical , sonication, glass bead mill, high pressure homogenization
  
• Filtration: Ultra-, Dia- and Microfiltration
  
• Membrane adsorption
  
• Chromatography: IEX, IMAC, HIC, SEC, RP, Affinity; 200µl – 4L column volumes, fully automated, packed bed and expanded bed absorption
  
• Formulation followed by lyophilization

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